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AnessentialroleforcomplementC5ainthepathogenesisofsepticcardiacdysfunction
...reasedejectionfraction,anddecreasedresponsetofluidresuscitationandcatecholaminestimulationduringthehypodynamicphase(5).Mostimportantly,myocardialdysfunctionputssepticpatientsathighrisktodevelopmulti-organfailure,whichisassociatedwithahighmortality.Multi-organfailureresultsfroma“viciouscycle“init...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第1期 -
DirectDetectionandIdentificationofMycobacteriumtuberculosisandMycobacteriumbovisinBovineSamplesbyaNovelNestedPCRAssay:CorrelationwithConv
...anddifferentiationofthesecloselyrelatedmycobacterialspecieswouldhelptodeterminethesource,reservoirsofinfection,anddiseaseburdenduetodiversemycobacterialpathogens.TheutilityofthehupBgene(Rv2986cinM.tuberculosis,orMb3010cinM.bovis)todifferentiateM.tuberculosisandM.boviswasevaluatedbyaPCR-restrictionfr...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第11期 -
AnalysisofGenomicDownsizingontheBasisofRegion-of-DifferencePolymorphismProfilingofMycobacteriumtuberculosisPatientIsolatesRevealsGeographicP
...icatingtheirpossibleancientorigin.RD9wasthemostconservedregion,RD11waspredominantlydeleted,andRD6wasthemostvariableamongtheisolatesinourcollectionirrespectiveoftheirgeographicregion.Incontrasttoearlierreports,ourresultsdemonstratethatthedeletionofRD1doesnotcorrelatewithadecreaseinthevirulencepotenti...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第12期 -
DetectionandIdentificationofEhrlichiaspp.inTicksCollectedinTunisiaandMorocco
...However,variantsofAnaplasma,provisionallydesignatedAnaplasma-like,werepredominantintheI.ricinustickpopulationinMaghreb.Otherwise,twovariantsofthegenusEhrlichiaweredetectedinI.ricinusandH.detritum.Surprisingly,avariantofWolbachiapipientiswasevidencedfromI.ricinusinMorocco.Theseresultsemphasizedthepot...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第3期 -
-Arrestin-DependentSpontaneous1a-AdrenoceptorEndocytosisCausesIntracellularTransportationof-BlockersviaRecyclingCompartments
...curin-arrestin-deficientcells;wasblockedorreversedbyanother1ligand,phentolamine,indicatingittoreflectbindingtotheorthostericrecognitionsite;andwaspreventedbyblockingclathrin-mediatedendocytosis.Theligandshowedrapid,diffuse,low-intensity,surfacebinding,supersededbypunctateintracellularbindingthatdeve...
医源资料库；在线期刊；分子药理学杂志；2005年第67卷第4期 -
MultispacerTypingTechniqueforSequence-BasedTypingofBartonellaquintana
...wedustoproposeagenome-widesequence-basedtypingmethod.Toensuresequencediscriminationbasedonhighlypolymorphicareas,weamplifiedandsequenced34spacersinalargecollectionofB.quintanaisolates.Sixoftheseexhibitedpolymorphismsandallowedthecharacterizationof4genotypes.However,thestrainvariantssuggestedbythenon...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第1期 -
TheAminosteroidPhospholipaseCAntagonistU-73122(1-[6-[[17--3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione)PotentlyInhibitsHuma
...rt,GermanyAbstractU-73122(1-[6-[[17--3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione)isawidelyusedantagonistofphosphoinositide-specificphospholipaseC(PLC)andisfrequentlyusedtodefinearoleofPLCinreceptor-mediatedelevationofintracellularcalciumconcentration([Ca2+]i).Inhumanpolymo...
医源资料库；在线期刊；分子药理学杂志；2005年第67卷第5期 -
AntithromboticEffectofaProtein-TypeIClassSnakeVenomMetalloproteinase,Kistomin,IsMediatedbyAffectingGlycoproteinIb-vonWillebrandFactorIntera
...P)Ib-IX-Vmediatesplateletactivationintheearlystageofthrombusformation.Kistomin,asnakevenommetalloproteinase(SVMP)purifiedfromvenomofCalloselasmarhodostoma,hasbeenshowntoinhibitvWF-inducedplateletaggregation.However,itsactionmechanism,structure-functionrelationship,andinvivoantithromboticeffectsarest...
医源资料库；在线期刊；分子药理学杂志；2007年第69卷第10期 -
人工髋关节置换并发假体周围骨折的临床分析
【摘要】分析人工髋关节置换术中、术后发生假体周围骨折的原因，探讨其预防措施和治疗方法。［方法］自1995年7月～2006年8月，共640例人工髋关节置换术患者，其中18例发生假体周围骨折，术中骨折11例（股骨距骨折7例，假体...
医源资料库；在线期刊；中国矫形外科杂志；2007年第15卷第20期 -
DevelopmentofaGeneral-Primer-PCR-Reverse-Line-BlottingSystemforDetectionofBetaandGammaCutaneousHumanPapillomaviruses
...CRpositivein21and6cases,respectively,withHPVtype5(HPV5)andHPV8beingthepredominanttypes.Thedataindicatethatthismethodcanbeavaluable,user-friendlytoolforthedetectionandtypingofcutaneousHPVinclinicalspecimensandmayhaveimplicationsforfuturemonitoringofvaccinesoralternativetreatmentmodalitiesfordiseasesc...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第11期