DevelopmentofNonsteroidalAnti-InflammatoryDrugAnalogsandSteroidCarboxylatesSelectiveforHumanAldo-KetoReductaseIsoforms:PotentialAntineoplastic
...yofPennsylvaniaSchoolofMedicine,Philadelphia,PennsylvaniaAbstractHumanaldo-ketoreductases(AKRs)regulatenuclearreceptorsbycontrollingligandavailability.Enzymesimplicatedinregulatingligandoccupancyandtrans-activationofthenuclearreceptorsbelongtotheAKR1Cfamily(AKR1C1-AKR1C3).Nuclearreceptorsregulatedby...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第1期Cyclicalesotropiafollowingsurgeryforpartiallyaccommodativeesotropia
...RS,UK;russellandsuzie.drummond@virgin.netAcceptedforpublication26August2003Keywords:esotropiaCyclicstrabismusisararephenomenoncharacterisedbyrecurringperiodsofheterotropiausuallyonalternatedays.ItwasfirstdescribedbyBohmin18451andclassicallyfollowsa48hourcyclewith24hoursof“straight“eyesfollowedby...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第6期Dietaryglycemicload,overallglycemicindex,andseruminsulinconcentrationsinhealthyschoolchildren
...lesofGLorOGI.Inagreementwiththesignificantlyhigherenergyandcarbohydrateintakesfoundintheboysthaninthegirls,GLvaluesweresignificantlyhigherintheboysthaninthegirls,buttheboysandthegirlsdidnotdiffersignificantlyinOGI.Mean(±SD)valuesofGLandOGIwere145±37and58±2,respectively.Thedistribution...
医源资料库;在线期刊;美国临床营养学杂志;2004年79卷第2期EvidenceforAgeandSexDifferencesintheSecondaryPreventionofStrokeinScottishPrimaryCare
...urpose—Secondarypreventivemeasuresplayanimportantroleinthereductionofstroke,thethirdlargestcauseofdeathinScotland.Weinvestigatedwhethersex,age,ordeprivationdifferencesexistedinthesecondarypreventionofstrokeinprimarycare.Methods–Aretrospectivecross-sectionalstudyusingacomputerizeddatabasewith61pr...
医源资料库;在线期刊;中风学杂志;2005年第36卷第8期昆明动物所Leber遗传性视神经病变合作研究取得新进展
...对近期早老素相关菱形样蛋白(presenilins-associatedrhomboid-like,PARL)基因单核苷酸多态(SNP)影响LHON发病的报道,研究人员在携带有m.11778GA突变的国人LHON患者、疑似患者和正常对照群体中进行了验证。结果未能在该病人群体中证实...
行业资讯;临床快报;神经科我国公立医院委托-代理问题探析
...委托人和代理人的双重身份,使得公立医院委托代理关系缺乏有效的激励、约束机制。优化医院的外部经营环境,创新医院的内部运营机制,尤其是进行审计委托关系链的重构,强化审计监督独立性,可在一定程度上解决我国公...
医源资料库;在线期刊;中华现代医院管理杂志;2007年第5卷第1期FamilialRiskofIschemicandHemorrhagicStroke
...Previousstudiesoffamilialriskshaveoftencombinedischemicandhemorrhagicstrokeeventhoughitseemsunlikelythatthese2verydifferentpathologicalconditionsareunderthesamegeneticinfluence.Thisstudyisthefirsttoinvestigatetheconcordant(samesubtype)anddisconcordant(differentsubtype)associationbetweenischemicandhe...
医源资料库;在线期刊;中风学杂志;2006年第37卷第7期CentralCompensationatShortMuscleRangeIsDifferentiallyAffectedinCorticalVersusSubcorticalStrokes
...tion,probablycentralinorigin.Thesepatternsarepresumedtobedeficientafterstroke.Weexaminedtheexcitabilitymuscle-lengthrelationinstrokepatientsandhealthycontrolsandhypothesizedaboutitsalterationinstrokepatients.Methods—Corticospinalexcitabilitywasassessedin31strokepatients(19subcortical,12cortical)an...
医源资料库;在线期刊;中风学杂志;2006年第37卷第8期Retinaltolerancetodyes
...fNeurophysiology,UniversityofCologne,GermanyCorrespondenceto:Priv-DozDrCLükeZentrumfürAugenheilkunde,Universit?tK?ln,Joseph-Stelzmann-Str9,D-50924K?ln,Germany;aia18@uni-koeln.deAcceptedforpublication2May2005ABSTRACTBackground:Dyesolutionsforintraoperativestainingofepiretinalmembranesandtheinternal...
医源资料库;在线期刊;英国眼科学杂志;2005年第89卷第9期ACC2005公布的临床试验的启示
...ndWomen‘sHospitalBoston,MAJamesFergusonMDAssociateDirector,CardiologyStLuke‘sEpiscopalHospitalandTexasHeartInstituteHouston,TXWomen‘sHealthStudyUseofaspirinforprimarypreventionCOMMITandCLARITYUseofclopidogrelinacute-MIpatientsTNTHigh-doseatorvastatininstableCHDpatientsASCOT-BPLACalciumchannelb...
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