低分子肝素和阿司匹林治疗不稳定型冠状动脉疾病的临床观察
...1.2方法观察组使用低分子肝素5000u于腹壁皮下注射,1次/12h,联合使用阿司匹林口服,发病后以前5天口服0.3g,每日1次,后改为75mg,每日1次。对照组用硝酸甘油10mg加入10%葡萄糖液500ml中,每日1次静脉点滴。 两组据病情需要...
医源资料库;在线期刊;中华医药杂志;2005年第5卷第8期GlycosylationoftheosmoresponsivetransientreceptorpotentialchannelTRPV4onAsn-651influencesmembranetrafficking
【摘要】WeidentifiedaconsensusN-linkedglycosylationmotifwithinthepore-formingloopbetweenthefifthandsixthtransmembranesegmentsoftheosmoresponsivetransientreceptorpotential(TRP)channelTRPV4.MutationofthisresiduefromAsntoGln(i.e.,TRPV4N651Q)resultedinlossofaslowermigratingbandonanti-TRPV4immunoblot...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期IdentificationofVariable-NumberTandem-RepeatLociinLeptospirainterrogansSensuStricto
LaboratoiredesSpirochetes,InstitutPasteur,ParisLaboratoireGPMS,InstitutdeGenetiqueetMicrobiologie,UniversiteParis-Sud,Orsay,FranceABSTRACTLeptospirainterroganssensustrictoisresponsibleforthemostfrequentandseverecasesofhumanleptospirosis.Theepidemiologyandclinicalfeaturesofleptospirosisareusuallyasso...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第2期ThePimkinasescontrolrapamycin-resistantTcellsurvivalandactivation
AbramsonFamilyCancerResearchInstituteandDepartmentofCancerBiology,UniversityofPennsylvania,Philadelphia,PA19104AlthoughPim-1orPim-2cancontributetolymphoidtransformationwhenoverexpressed,thephysiologicroleofthesekinasesintheimmuneresponseisuncertain.WenowreportthatTcellsfromPim-1–/–Pim-2–/–an...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第2期MMP13mutationcausesspondyloepimetaphysealdysplasia,Missouritype(SEMDMO)
...versityofOxford,OxfordCentreforDiabetes,EndocrinologyandMetabolism(OCDEM),ChurchillHospital,Oxford,UnitedKingdom.2DepartmentofMedicine,HarvardMedicalSchool,andtheCenterforImmunologyandInflammatoryDiseases,MassachusettsGeneralHospital,Boston,Massachusetts,USA.3DepartamentodeBioquímicayBiologíaMolec...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第10期EvaluationofReal-TimeReverseTranscriptasePCRandReal-TimeLoop-MediatedAmplificationAssaysforSevereAcuteRespiratorySyndromeCoronavirusDetection
DepartmentofMicrobiology,QueenMaryHospitalDivisionofInfectiousDiseases,CentreofInfection,UniversityofHongKong,HongKong,SpecialAdministrativeRegion,People‘sRepublicofChinaABSTRACTWecomparedtheperformanceofarecentlyestablishedreal-timeloop-mediatedamplification(LAMP)assaywiththeonefromahighlysensiti...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第7期基层医院无心肌酶检测条件下对不典型心肌梗死的诊治
...液+硝酸甘油等综合治疗。2天后疼痛渐缓停止。入院后48h体温开始升高。波动于37.5℃~38.5℃之间,持续6天自然消退。入院48h化验,WBC13.6×109/L,N0.80,L0.20;ESR60mm/h;肝功:谷丙转氨酶(ALT)60U/L,余正常。入院后多次复查心电图V1~...
合作平台;在线期刊;中华中西医杂志;2004年第5卷第24期;经验交流Denys-Drash综合征及其致病基因突变鉴定二例报道
...病杂志2006Vol.22No.7P.383-38713(北京)为了研究中国Denys-Drash综合征(DDS)患者Wilms瘤基因1(WT1)的基因突变。研究者应用PCR方法扩增出WT1基因全部10个外显子及其相邻内含子序列,经纯化后进行PCR产物直接测序。结果2例患者WT1基因分别...
行业资讯;临床快报;遗传与基因组EarlyG2/Mcheckpointfailureasamolecularmechanismunderlyingetoposide-inducedchromosomalaberrations
...inalcitation:J.Clin.Invest.116:80-89(2006).doi:10.1172/JCI25716Citationforthiserratum:J.Clin.Invest.116:2306-2307(2006).doi:10.1172/JCI25716E1Duringthepreparationofthemanuscript,errorswereintroducedinthelabelsofFigure3EandFigure6A.Thecorrectedfiguresareprovidedbelow.Weregretthiserror.Figure3FISHanal...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第8期DesignofNovelConformationalandGenotype-SpecificAntigensforImprovingSensitivityofImmunoassaysforHepatitisCVirus-SpecificAntibodies
ChironCorporation,4560HortonSt.,Emeryville,California94608ABSTRACTThecurrentcommerciallylicensedenzyme-linkedimmunosorbentassays(ELISAs)forhepatitisCvirus(HCV)mainlyuserecombinantproteinscontaininglinearepitopes.Thereisevidence,however,thatconformationalepitopesofHCVaremoreimmunoreactive.Thus,wehave...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期