二、亚系的命名法

...达出来。　　（1）亚系符号写在品系符号后面，例如BALB/cf，DBA/2eB,C3H/Ha-p。其中C、2、Ha为亚系符号，亚系符号后面的符号f、e、p分别说明代乳，受精卵转输各突变种。　　（2）亚系符号后面记上处理过程或导入基因的符号，在...

Structure-ActivityRelationshipof1,4-DihydropyridinesasPotentiatorsoftheCysticFibrosisTransmembraneConductanceRegulatorChlorideChannel

【关键词】Structure-ActivityMutationsoccurringintheCFTRgene,encodingforthecysticfibrosistransmembraneconductanceregulatorchloridechannel,causecysticfibrosis(CF).MutationsbelongingtoclassII,suchasPhe508,giverisetoaproteinwithbothadefectivematurationandalteredchannelgating.Mutationsbelongingtocla...

磺胺嘧啶银

药品名称磺胺嘧啶银拼音名Huang’anMidingyin英文名SULFADIAZINESILVER来源(分子式)与标准本品为N-2-嘧啶基-4-氨基苯磺酰胺银盐。按干燥品计算，含C10H9AgN4O2S不得少于98.0％。性状　　本品为白色或类白色的结晶性粉末；遇光或遇热易变...

第五节　HLA的临床应用

...公式称归因危险（attributablerisk），又叫病因系数（etiologicfactor）,表示群体中病人组中有百分之多少归因于HLA：归因危险=B（R-1）/[B（R-1）+1]　　B为患者人群的百分率；R为相对危险率。如强直性脊椎炎的归因危险为0.89即患该病...

High-ResolutionComputedTomographyImagingofAirwayDiseaseinInfantswithCysticFibrosis

...CanadaABSTRACTRationale:Thedevelopmentofearlylungdiseaseinpatientswithcysticfibrosis(CF)remainspoorlydefined.Objective:DeterminewhetherasymptomaticinfantswithCFhaveevidenceforchangesinairwaystructurewhenassessedbyhigh-resolutioncomputedtomography,andwhetherairwaystructurecorrelateswithairwayfunction...

RelativecontributionofOATandOCTtransporterstoorganicelectrolytetransportinrabbitproximaltubule

...diolabeledChemicals(St.Louis,MO)orSigma(St.Louis,MO).6-Carboxyfluorescein(6CF)wassuppliedfromMolecularProbes(Eugene,OR;Leiden,TheNetherlands).TheFlp-InexpressionsystemandthemammalianexpressionvectorpcDNA3.1werepurchasedfromInvitrogen(Carlsbad,CA).AllotherchemicalswerepurchasedfromSigmaorfromothersta...

StructuralAnalogofSildenafilIdentifiedasaNovelCorrectoroftheF508del-CFTRTraffickingDefect

【关键词】StructuralTheF508delmutationimpairstraffickingofthecysticfibrosistransmembraneconductanceregulator(CFTR)totheplasmamembraneandresultsinapartiallyfunctionalchloridechannelthatisretainedintheendoplasmicreticulumanddegraded.Werecentlyusedanovelhigh-throughputscreening(HTS)assaytoidentify...

原发高血压患者脉压对血管内皮功能和大动脉缓冲功能的影响

...ividedinto3groupsbasedonthelevelsof24hmeanpulsepressure.Carotid-FemonalPWV(CF-PWV)andCarotid-RadialPWV(CR-PWV)weremeasuredbyautomaticpulsewavevelocitymeasuringsystem.Thebrachialarteryresponsetoflow-mediatedendothelium-dependentdilation(FMD)andnitroglycerin-mediateddilation(NTG-MD)wereevaluatedbytheh...

RiskFactorsforDeathofPatientswithCysticFibrosisAwaitingLungTransplantation

...o,Toronto,Ontario,CanadaABSTRACTRationale:Theoptimaltimingforlistingofcysticfibrosispatientsforlungtransplantationiscontroversial.Objectives:Weconductedaretrospectivecohortstudyof343patientslistedforlungtransplantationatfouracademicmedicalcenterstoidentifyriskfactorsfordeathwhileawaitingtransplantat...

醋酸磺胺米隆

药品名称醋酸磺胺米隆拼音名CusuanHuang’anmilong英文名MAFENIDEACETATE来源(分子式)与标准本品为α－氨基－对甲苯磺酰胺醋酸盐。含C7H10N2O2S.C2H4O2不得少于98.0％。性状　　本品为白色或淡黄色结晶或结晶性粉末；有醋酸臭；水溶液呈...