Noaudiblewheezing:nuggetsandconundrumsfrommouseasthmamodels
...ributionsofeosinophilsandmastcellsandthesensitivitytoinducedAHRinthecommonlyusedmousestrains.Wesuggestthatthesediscordances,reflectingmethodologicalandgeneticdifferences,maybeinformativeforunderstandingheterogeneityofhumanasthma.Humanbronchialasthmaisheterogeneousintermsofseverity,genetics,andinalll...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第12期巨淀粉酶1例的实验观察
...近,在普查中发现巨淀粉酶(Macroamylase,M-AMS)1例。对其血清用不同浓度的PEG-6000处理后,发现与急性胰腺炎阳性对照和正常人阴性对照比较有明显不同,现报告如下。 1临床资料 患者,女,63岁,因眩晕、颈椎病入院。...
合作平台;在线期刊;中华现代中西医杂志;2005年第3卷第2期;病例报告WorkloadDuetoAspergillusfumigatusandSignificanceoftheOrganismintheMicrobiologyLaboratoryofaGeneralHospital
...s95%CIarepresented.Weevaluatedthelinearincreaseintheprobabilityofinfectionbyusingthechi-squaretestfortrend.Thenullhypothesiswasrejectedineverycontrastofhypothesisforanalphaerrorof0.05.RESULTSFungalisolationandworkload.Duringthestudyperiod,therewere188,374hospitaladmissions,andthemicrobiologylaborato...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第5期Mappingquantitativetraitlociinhumans:achievementsandlimitations
...aledunforeseencomplexitiesandhaveresultedinmanyfailures(5-6),andtherearemanyunresolvedissuespertainingtostudydesignandstatisticalanalyses(7-8).Inhumans,andinotheroutbredspecies,QTLmappinghasonlyhadlimitedsuccess(seeTastesensitivitytophenylthiocarbamideforasuccessstory).Inthisreview,weshallfocusonlyo...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第6期Hypoxia-inducedneutrophilsurvivalismediatedbyHIF-1–dependentNF-Bactivity
...rophageandRF/6Aretinallines(41,42),yetinteractionsbetweenHIFandNF-Barepoorlyunderstood.StudieslookingatthenonhypoxicinductionofHIFhaveshownanumberofindirectlinksbetweentheHIFandNF-Btranscriptionpathways.Inneuronalcells,aHIF-dependentup-regulationoferythropoietinhasbeendescribedtopreventexcitotoxin-i...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第1期急性胰腺炎患者尿胰蛋白酶原Ⅱ的检测意义
急性胰腺炎(AP)是常见的腹部疾病。常规测定血/尿α-淀粉酶(α-AMS)是诊断AP的主要实验方法,但约19%的病例无高淀粉酶血症,所以作为筛选项目其敏感性较差。而检测患者的尿胰蛋白酶原Ⅱ(TSGⅡ),能特异地反映胰腺坏死...
合作平台;在线期刊;中华实用医药杂志;2005年第5卷第4期;检验与临床NO/redoxdisequilibriuminthefailingheartandcardiovascularsystem
...chanismsbywhichRNSandROSmodulatecellularsignaltransductionremainincompletelyunderstood,thereisageneralconsensusthatcysteineresiduesareprincipalsitesofredoxregulation(10,13,14).CrosstalkbetweenROS-andRNS-regulatedpathwaysmayoccuratboththechemicalinteractionlevel(15,16)andthroughtheircoordinateeffects...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第3期大剂量胺碘酮静脉注射在顽固性心动过速和室颤
...心动过速和(或)室颤中的临床应用中国医学科学院阜外心血管病医院急症抢救科袁贤奇宋有城朱俊王国干贺丽霞谭慧琼杨艳敏康连鸣郝云霞目的总结大剂量胺碘酮(AmidaroneAm)静脉注射治疗顽固、持续室性心动过速(VT)和(或)心...
医源资料库;医学文档库;心血管相关几种检验结果降低的临床意义
...理性降低病毒性肝炎、酒精性肝炎、甲状腺功能亢进、败血症、感染性心内膜炎以及结缔组织病、长期卧床患者均可使CK活性降低。酒精性肝病患者CK降低与尿肌酐排泄率下降有关,败血症、感染性心内膜炎可能由于血中中性白...
医源资料库;在线期刊;中华医学研究杂志;2006年第6卷第4期PropertiesandprotectivevalueofthesecondaryversusprimaryThelpertype1responsetoairborneMycobacteriumtuberculosisinfectioninmice
...enteredthelungsatsitesofinfection.Thisaspectoftheanti-Mtbresponseiscurrentlyunderstudyinthislaboratory.Resultsobtainedthusfar(unpublisheddata)indicatethatthenumberofMtb-specificTcellsinthedrainingnodeatanyonetimeofinfectionisconsiderablysmallerthanthenumberinthelungs.Moreover,becauseithasbeendemonst...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第12期